Safety pharmacology studies help in identifying preclinical adverse drug reactions. Cassia now generally includes the largest species of … Cassia auriculata belonging to Caesalpiniaceae (Fabaceae) is common plant in India, widely used in Ayurveda medicine as a tonic and remedy for diabetes. Cassia auriculata flowers Having known the pharmacological significance Cassia auriculata, an earnest attempt has been made to SUMMARY. Effect of aqueous and ethanol extracts of Cassia auriculata L. flowers 102 0 20 40 60 80 100 120 A q u eo u s ic ex tr t E th ano l e xt r a c t Antioxidant activity (%) Figure 1: Antioxidant activity of aqueous and ethanol extract of C. auriculata flowers Data were presented as mean ± SD of each three replicates All three plants were only effective against the Gram-positive bacteria. The aerial parts of CA were subjected to solvent extraction, and the extracts were fractionised by gas chromatography and mass spectrometry analysis for its phytochemical content. 7172-.7274 e-ISSN:2581-6063 (online), ISSN:0972-5210 ANTICANCER ACTIVITY OF TAMARINDUS INDICA FRUIT PULP AND CASSIA AURICULATA LEAVES EXTRACT AGAINST BREAST CANCER CELL LINE P. Durga1, R. Malarkodi2, D. Sudha3, C. Shamaila Afreen4 and Anooj E.S.5* 1,2,4PG and Research Department of Biochemistry, Marudhar Kesari Jain … The phytochemical screening and antioxidant activity were made in these extracts. The ethanol and methanol extracts of Cassia auriculata flowers were screened for antioxidant activity. Mol Cell Biochem 2003;243:23-8. Cassia auriculata ESBL are plasmid mediated enzymes which are capable of commonly known as tanners Cassia, also known as hydrolyzing and inactivating a wide variety of-lactams “Avaram” in Tamil is a shrub that belongs to the including third generation cephalosporins (3GC),Caesalpiniaceae family [13]. It is one of the main constituents of ‘Kalpa herbal tea ’and has proven antidiabetic action [3]. Cassia auriculata leaves were collected from Srirangapatnam, Mysuru, Karnataka, India, (Geographical Coordinates: 12.4237 N, 76.6829 E) in October 2019. The plants produces flowers in … The fresh and young leaf samples of Cassia auriculata was collected, washed thoroughly with sterile double distilled water (DDW) and surface sterilized with 0.1 % HgCl2 for 2 - 3 min under the hood of laminar air flow. 2, 2020 pp. Cassia auriculata is frequently used for the treatment of infections, pathologies of the skin disease, fever, liver injury and others diseases involving inflammation and pain. Thin-layer chromatography The TLC studies of the ethanol extract of Cassia auriculata showed the presence of well-separated The powder of the herb, mixed with honey is equally efficacious in such a case. Pari L, Latha M. Effect of Cassia auriculata flowers on blood sugar levels, serum and tissue lipids in streptozotocin diabetic rats. The plant has been reported to antibacterial, hypoglycemic and microbicidal activity The It is widely used in Pharm. The plant was unambiguously identified by Dr. Murali Mahadevamurthy. Cassia is an indigenous medicinal plant genus, in which Cassia auriculata have large biodiversity in south India and Cassia fistula in north India. Cassia auriculata is a natural herb belongs to family Fabaceae and locally called as ‘avaram’. the antibacterial properties of flowers of Cassia auriculata. The shrub is specially famous for its attractive yellow flowers which are used in the treatment of skin disorders and body odour. The present study is an attempt to evaluate the in vitro anti-inflammatory and in silico anticancer potentials of the plant Cassia auriculata (CA). Thus, prepared extracts were subjected to phytochemical investigation and evaluated for antioxidant effect using DPPH and antisolar efficacy. Cassia auriculata is used in Ayurvedic medicine as “Avarai Panchaga choornam” (mixture of five parts of the shrub i.e. The leaves are bitter, astringent, acrid, thermogenic, haematinic, constipating and expectorant; seeds are The Cassia V. Kavimani et al J. Chem. C. auriculata was found to be 10.20% w/w. The qualitative phytochemical analysis of the extract showed the presence of flavonoids, alkaloids, tannins, glycosides, terpenoids, phenols, carbohydrates, and proteins. Cassia auriculata Linn. Cassia auriculata, commonly known as “Tanner’s cassia,” is widely used in Indian folk medicine for the treatment of diabetes mellitus. In tune with this effort, the objective set for the present investigation is to estimate the phenolic and flavonoid contents in flower extracts of Cassia auriculata and Cassia siamea. The plant is mainly valued for its cathartic properties and is specially useful in habitual constipation. commonly known as ‘Tanner’s Cassia’ (Ceasalpinaceae) or Avartaki in Ayurveda is an annual or biennial shrub found throughout India in open forests. Abstract: Objectives: The present study deals with an in-vitro screening for the anti-solar potential of aqueous and ethanolic extracts of Cassia auriculata using the UV method.Methods: Aqueous and ethanolic extracts were prepared. In the present study, the antioxidant activity of C. auriculata aqueous leaf extract (CLEt) was evaluated in streptozotocin-induced mild diabetic (MD) and severe diabetic (SD) rats. The antioxidant activity was determined by an improved assay based on the decolorization of the radical monocation of 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. It is shrub, having smooth bark and mostly seen in the India, Sri Lanka and other Asian countries. Keywords: Cassia auriculata, Phytochemical compounds, Pharmacological activity and PASS prediction. Cassia auriculata Linn., belonging to the family Caesalpiniaceae, is commonly known as Tanner’s cassia. Cassia auriculata , Linn (Caesalpiniaceae) commonly known as Tanners Cassia [Avaram] is a shrub with large bright yellow flowers, growing wild in Central Provinces and Western peninsula parts of India [2] . These leaves are mainly used to treat anthelmentic infections, ulcer, leprosy and other skin diseases. 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