Patients treated with the tomato extract also had reduced sputum neutrophil elastase activity.77 In a murine model of asthma, lycopene suppressed infiltration of inflammatory mediators and cells into the lung; decreased airway hyperresponsiveness; and inhibited cell infiltration and invasion.78 Lycopene may also have a role in reducing rhinovirus-induced airway inflammation by potentially inhibiting the formation of reactive oxygen species and decreasing viral replication.79. However, lycopene is POSSIBLY … Elimination of 1 study with wide confidence intervals revealed a significant inverse association between dietary intake as well as blood concentrations of lycopene and prostate cancer risk.108 A meta-analysis of 21 studies provided further evidence of diets rich in tomatoes providing protection against prostate cancer.19 In a Cochrane review of randomized controlled trials of lycopene for the prevention and treatment of benign prostatic hyperplasia and prostate cancer, only 3 of 64 published studies with 154 participants met inclusion criteria. Lycopene protected against cancer by activating cancer-preventive phase 2 enzymes.19, 27, Growing evidence exists for the use of lycopene in prostate cancer prevention. Lycopene administered as a pure compound has been studied in clinical trials at dosages of 8 to 75 mg/day.66, 80, 81, 82, 83, 84 Lycopene is primarily available in capsule and softgel form, with dosage guidelines from manufacturers ranging from 10 to 30 mg taken twice daily with meals. After viewing product detail pages, look here to find an easy way to navigate back to pages you are interested in. Lycopene suggested uses include for cancer, preventing atherosclerosis, cardiovascular disease, prostate cancer, human papillomavirus infection, cataracts, asthma, antioxidant, and as an anti-inflammatory.. Promotes Heart Health Menopause and Bone Health Support. Daily supplements containing up to 120 mg of lycopene have been used safely for up to one year. One trial reported a cancer-related hemorrhage in a patient taking lycopene, but causality was unclear. Scientific literature documents lycopene’s antioxidant activity and its use in cancer prevention (breast and prostate), as well as its use in the prevention of cardiovascular disease. turmeric, saw palmetto, Ginkgo Biloba, garlic, echinacea. Avoid use with hypersensitivity to lycopene or to any of its food sources, especially tomatoes. Lycopene Claims The Science (or Lack Thereof) Behind Lycopene Word on the Street About Lycopene The Bottom Line: Are Lycopene Supplements Worth a Try? Those aside, there are zero additional ingredients, making this an excellent choice for lycopene. Get info of suppliers, manufacturers, exporters, traders of Lycopene Capsule for buying in India. Improvements were progressive and were observed in several scores at 1 month and in all scores at 3 months.102 The sponsor-funded, double-blind, randomized PROCOMB Italian multicenter trial determined that the combination of saw palmetto, lycopene, selenium (Profluss) plus tamsulosin produced significantly improved prostate symptom scores and Qmax (flow) after 1 year of treatment compared with Profluss or tamsulosin monotherapies in 219 men with BPH/lower urinary tract symptoms.105. Lycopene is also incorporated in multivitamin and multimineral products. This information should not be used to decide whether or not to take this product. The powerful antioxidant properties of lycopene fight free radicals and oxidative stress. Lycopene extract is usually low in cost and readily available in most health food stores. In a review of epidemiologic studies, a diet rich in fresh tomatoes, tomato sauce, and pizza reduced the incidence of prostate cancer in a cohort of 40,000 men.19 Increased consumption of tomatoes statistically lowered the risk of prostate cancer in a cohort of 14,000 Seventh-day Adventist men.4, 28 A 2015 systematic review and dose-response meta-analysis of observational studies evaluating dietary intake (n = 13 studies) or blood concentrations (n = 15 studies) of lycopene on the risk of prostate cancer found a reduction in risk by 3% per 1 mg/day increment of dietary intake of lycopene. This product may be unsafe when used before surgery or other medical procedures. Lycogard Capsule is used for Vitamin a deficiency, Leg pain due to blocked arteries, Skin diseases, Skin infection, High blood pressure, For eye and ear wash, Uterine cancer, Red blood cell production, Eye problems, Wound healing and other conditions. One report found beta-carotene to be active in wound healing, while lycopene was inactive.62 Other studies document that lycopene or tomato-derived products rich in lycopene provide photoprotective effects against ultraviolet light-induced erythema.63, 64, 65 Higher levels of lycopene antioxidants in the skin effectively led to lower levels of skin roughness.15 In a placebo-controlled study, lycopene effectively managed oral lichen planus.66, In some animal models, lycopene reduced diabetes-induced learning and memory impairment by decreasing oxidative stress and inflammation.67 Lycopene may also attenuate diabetic neuropathic pain by inhibiting action of tumor necrosis factor (TNF)-alpha and nitric oxide.68 Lycopene may be useful in patients with type 2 diabetes by suppressing oxidative stress and enhancing innate immunity or serum levels of immunoglobulin M.69, Reports are available in the International Symposia on Lycopene and Tomato Products in Disease Prevention.70, 71 Reviews describing lycopene and disease prevention are also available.72, 73, 74, 75, Epidemiological studies have found that lycopene decreased the inflammation marker C reactive protein.13 The production of inflammatory mediators, such as TNF-alpha, was reduced in patients consuming a tomato-based drink.76 Asthmatic adults receiving lycopene treatment experienced improvement in airway inflammation. Only 1 study reported incidence of prostate cancer (10% vs 30% in the lycopene vs control groups).29 Another review of 8 randomized controlled trials found study quality varied significantly, making conclusions impossible.30 Lycopene also inhibited the progression of benign prostate hyperplasia.33 Lycopene concentrations changed rapidly in men with prostate cancer given lycopene supplements for several weeks prior to radical prostatectomy. Puritans Pride Lycopene 20 Mg Softgels, 60 Count, Puritan's Pride Lycopene 40 mg, Supplement for Prostate and Heart Health Support**, Contains Antioxidant Properties**, 60 Rapid Release Softgels, Jarrow Formulas CarotenAll for Cardiovascular and Vision Health, 60 Soft gels, Puritans Pride Lycopene 10 Mg Softgels, 100 Count, NOW Supplements, Lycopene 20 mg with Natural Extract from Tomatoes, Free Radical Scavenger*, 50 Softgels, Lycopene & Lutein Complex 50MG 200 Veggie Capsules (Non-GMO & Gluten Free) Antioxidant Natural Tomato Great for Prostate Health, Immune System Support, Heart Health, Eyesight Support, NOW Supplements, Lycopene 10 mg with Natural Extract from Tomatoes, Free Radical Scavenger*, 60 Softgels, Lycopene 20mg Per Serving - 200 Capsules - Lycopene Supplement - Super Antioxidant which Helps Support Immune System and Prostate Health, Swanson Lycopene Supplement, Prostate Health Supplement 20 mg, 60 Softgels, Healthy Origins LYC-O-Mato Lycopene (Non-GMO) 15 mg, 180 Softgels, Lycopene 50mg 180 Vegetarian Capsules | Supplement for Prostate & Heart Health | Antioxidant Natural Tomato Extract Non-GMO | Supports Immune System & Helps Reduce Free Radical Damage - Pure Powder, Spring Valley - Lycopene 10 mg, 60 Softgels, Life Extension Mega Lycopene Extract 15 Mg, 90 softgels (00455), 2 Bottles Lycopene 50mg 180 Total Capsules KRK Supplements, Lycopene 50mg x 180 Tablets (6 Months Supply). Non GMO by Jiva Botanicals, Jarrow Formulas Lyco-Sorb, Supports Prostate & Cardiovascular Health, 10 mg, 60 Softgels, 50mg Lycopene x 360 Tablets (2 Bottles of 180 Tablets Each - 12 Months Supply). Manufacturer of Capsules - Prebiotic & Probiotic, 100 % Lycopene With Multi Vitamin, Calcium Carbonate 200mg Alphacalcidol 0.25mcg and Silymarin B-Complex … This is only a brief summary of general information about this product. For years, scientists noted that diets high in beta-carotene FROM FOOD SOURCES, reduced risk of many types of cancer, including lung cancer in smokers. Post-hoc analysis demonstrated a positive dose-response correlation between lycopene concentration and absolute change in EDV response between visits (P = 0.019). Like beta-carotene, lycopene is a carotenoid. Certain groups, like people on blood-thinning or blood pressure medications and pregnant women, should avoid using lycopene from dietary supplements. Tomato-based products are acidic and may irritate stomach ulcers. Gardian Capsules is mainly associated with symptoms and indications-The International Classification of Diseases (ICD)- A11AA03-Multivitamins and … 300% Strength of Regular Lycopene Tablets. Lycopene intake and decreased cancer risk association has been observed in stomach cancers.37 Lycopene's protective role in the early stages of cervical carcinogenesis was noted in 1 study.38 Plasma levels of lycopene and other carotenoids were lower in women with cervical intraepithelial neoplasia and cervical cancer, suggesting a protective effect of higher lycopene concentrations.39, 40, Lycopene was more efficient than any carotenoid in inhibiting insulin-like growth factor type 1 (ie, high levels of this growth factor are related to an increased risk of cancer) in patients with a higher risk of colorectal cancer.31, 32 A meta-analysis of observational studies explored lycopene consumption and associated risk of colorectal cancer. Apoptotic activity was observed and may have been caused by lycopene.34 Prostate volume was reduced in prostate cancer patients taking 30 mg/day of lycopene extract for 3 weeks prior to radical prostatectomy.34 In 997 middle-aged men, an inverse association was found between serum lycopene levels and overall cancer incidence. There is some science behind what lycopene is chemically and why it is the color it is. Lycopene is responsible for the bright red color in certain foods such as tomatoes. What Is Lycopene? One cup of canned tomato paste provides 75 mg of lycopene, compared to 5 mg in one cup of raw tomatoes, the Linus Pauling Institute notes. Lycopene is a carotenoid − a natural pigment that gives some vegetables and fruits their red color. Tomato consumption does increase lycopene concentrations in the breast milk and plasma of lactating women.97. Fat also enhances the absorption of lycopene. Some GI complaints (eg, diarrhea, dyspepsia, gas, nausea, vomiting) are documented. There is no association between lycopene and the risk of bladder and colon cancers.. Top subscription boxes – right to your door, © 1996-2020, Amazon.com, Inc. or its affiliates. There are several published studies that evaluate whether lycopene in tomato products or supplements could have protective effects against prostate cancer and cardiovascular disease. The amount of lycopene in food is assumed to be safe. May being the operative word. Tomato-based products and lycopene supplements are generally well tolerated. This information is not specific medical advice and does not replace information you receive from your health care provider. Diets rich in carotenoids like lycopene are generally associated with a decreased risk of certain types of cancers. 50mg Lycopene x 360 Tablets (2 Bottles of 180 Tablets Each - 12 Months Supply). No toxic effects were observed in rats treated with lycopene 2,000 mg/kg/day for 28 days, an intake similar to approximately lycopene 200 mg/kg of body weight per day in humans.86 Another 13-week toxicity study generated similar results. Also find here related product comparison | ID: 21312970688 Our most popular products based on sales. Other sources include apricots, cranberries, grapes, pink grapefruits, guavas, papayas, peaches, and watermelons.2, In North America, nearly 85% of dietary lycopene is derived from tomatoes and tomato-based products.1 Tomatoes have been cultivated since the 16th century as a food source. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Scientific Name(s): Psi-carotene, PsiCommon Name(s): Lycopene. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Prime members enjoy FREE Delivery and exclusive access to music, movies, TV shows, original audio series, and Kindle books. They combat inflammation, thereby preventing serious ailments like cancer and heart disease. Natural sources primarily contain the all-trans form of lycopene; the cis form of lycopene is more bioavailable and is less likely to precipitate and form crystals.11, 12. As a result of this striking color, it is actually approved for use as a food coloring. Lycopene is an antioxidant. Lycopene is lipophilic and insoluble in water. Triple Strength Lycopene are 3 x Strength of Regular Tablets. One trial documented a cancer-related hemorrhage in a patient taking lycopene, but causality was unclear.98 Tomato-based products are acidic and may irritate stomach ulcers. Lycopene is a powerful antioxidant, which means that, among nutrients, it has a greater-than-average ability to “quench” free radicals that cause damage to cells. Co-Enzyme Q10, Lycopene, Omega 3 Fatty Acid, Selenium, DHA, EPA, L-Carnitine And L-Tartrate Capsules - Buy Coenzyme Q10 at best price of Rs 50000/box from Innervate Lifesciences (A Unit Of Asvins Lifecare). Tomato consumption increases lycopene concentration in the breast milk and plasma of lactating women. Although numerous animal studies exist,4 only clinical evidence was reviewed in the following studies. Lycopene is also incorporated in multivitamin and multimineral products. There are numerous studies on the uses of lycopene in treating cancer and cardiovascular disease, as well as on its antioxidant and anti-inflammatory activity. Lycopene was well tolerated; no serious adverse events were reported.106, A meta-analysis of 13 observational studies (n =18,999) evaluated the association between blood levels of antioxidants and vitamins to the risk of age-related cataract. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Lycopene absorption in humans is approximately 10% to 30%, with the remaining excreted.1 The half-life elimination of lycopene in plasma was estimated to be 12 to 33 days, while a single-dose pharmacokinetic study documented 28 to 61 hours.85 The estimated daily dietary intake of the general population is 0.5 to 27 mg per person per day.86 Factors affecting uptake and absorption of carotenoids have been reported.87 Pharmacokinetic parameters of lycopene have been evaluated in humans.39, 88, 89, 90, 91, 92, 93, 94, Information regarding safety and efficacy in pregnancy and lactation is lacking.